REGIONALISATION OR MARGINALISATION? THE CASE OF THE OROMO LIVING IN AMHARA REGION OF ETHIOPIA



mRNA-delivery of IDO1 suppresses T cell-mediated autoimmunity

Summary: Indoleamine-2,3-dioxygenase (IDO)1 degrades tryptophan, obtained through dietary intake, into immunoregulatory metabolites of the kynurenine pathway.Deficiency or blockade of IDO1 results in the enhancement of autoimmune severity in rodent models and increased Boys Sun Shirt susceptibility to developing autoimmunity in humans.Despite this,

read more


Immunogenicity of novel vB_EcoS_NBD2 bacteriophage-originated nanotubes as a copyright for peptide-based vaccines

Non-infectious virus-like nanoparticles mimic native virus structures and can be modified by inserting foreign protein fragments, making them immunogenic tools for antigen presentation.This study investigated, for the first time, the immunogenicity of long and flexible polytubes formed by yeast-expressed tail tube protein gp39 of bacteriophage vB_E

read more